[Skip to Content]
[Skip to Content Landing]
December 6, 2000

Slow Wave Sleep and Release of Growth Hormone—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor

JAMA. 2000;284(21):2717-2718. doi:10.1001/jama.284.21.2717

In Reply: We found that the chronology of aging of GH release in healthy adult men follows a pattern remarkably parallel to that of SW sleep. Our analysis further indicated that lower amounts of SW sleep, independent of age, partly account for reduced GH secretion in midlife and late life. These data add to a large body of evidence from studies in both humans and rodents indicating that common mechanisms underlie SW sleep generation and GH release during adulthood.1