Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor
To the Editor: Although I applaud the effort
by Dr Williams and colleagues1 to recognize
and treat depression in elderly patients, I am concerned about their choice
of paroxetine for this study population. Patients enrolled in this study had
a mean age of 71 years. Patients with moderate or severe cognitive impairment,
as defined by a Folstein Mini-Mental State Examination (MMSE) score of 23
or less, were excluded. A low MMSE score is a nonspecific finding and could
indicate either dementia or delirium.
Leard-Hansson J. Treatment of Mild Depression in Elderly Patients. JAMA. 2000;284(23):2993–2994. doi:10.1001/jama.284.23.2993
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