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December 20, 2000

Acute Myocardial Infarction and Prior Antibiotic Use

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Executive Deputy EditorIndividualAuthor

JAMA. 2000;284(23):2998-2999. doi:10.1001/jama.284.23.2993

To the Editor: Chronic infections, particularly with Chlamydia pneumoniae, may contribute to the development of atherosclerosis. Use of fluoroquinolones and tetracyclines has been associated with protection against myocardial infarction (MI).1 We performed a case-control study to determine whether patients receiving antibiotics effective against C pneumoniae were less likely to have been admitted for a first acute MI.