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January 3, 2001

Oral Contraceptives and Risk of Breast Cancer in Women With a Family History of Breast Cancer—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor

JAMA. 2001;285(1):39-40. doi:10.1001/jama.285.1.39

In Reply: Dr Kirkland raises an important issue regarding OC formulations, like Enovid, that contained especially high doses of estrogens. The problem, from an epidemiologic perspective, is the accuracy of recall about specific brands and formulations. Recent research has found that women are able to recall ever or never use and age of use, but not specifics—even when prompted with picture cards of possible brands.1,2 Thus, we made no attempt to obtain such specific information. We agree, however, that such detailed information could help clarify this important issue.