To the Editor: Norman Cousins1 originally reported that only 10 minutes of laughter alleviated the pain of ankylosing spondyilitis. Subsequently, it has been reported that laughter during a 60-minute humorous video decreased blood cortisol levels and increased natural killer activity in healthy subjects.2 Another study reported that exposure to a 60-minute rakugo (traditional Japanese comic story) decreased blood levels of interleukin 6 and interferon γ and alleviated pain in patients with rheumatoid arthritis.3