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April 11, 2001

Handheld Cellular Telephones and Brain Cancer Risk—Reply

Author Affiliations

Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001

JAMA. 2001;285(14):1838-1839. doi:10.1001/jama.285.14.1838

In Reply: Dr Kane suggests that exclusion of case patients with high mortality resulted in biased findings. A patient's condition and ability to participate is not necessarily related to the aggressiveness of the tumor itself but could reflect comorbidity. Bias could result if cellular telephone use is related only to advanced tumor stage or high morbidity, although very few studies suggest that risk factors are related primarily to the aggressiveness of tumors and not to their origin. Glioma transplantation studies in animals showed no increase in tumor size with exposure to radiofrequency fields.1

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