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May 2, 2001

Outcomes of a Trial of HIV-1 Immunogen in Patients With HIV Infection

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;285(17):2191-2195. doi:10.1001/jama.285.17.2191

To the Editor: Dr Kahn and colleagues1 claimed that after a disagreement between them and the sponsor, they published the incomplete, although generally negative, results of a trial of an immunologic modifier (Remune; The Immune Response Corp [IRC], Carlsbad, Calif) for human immunodeficiency virus (HIV) "to fulfill our responsibility to inform patients of the outcome of this study, and to contribute to their understanding of HIV-1 Immunogen if it was to be studied in another clinical trial." I find that the article is inconclusive for several reasons.