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May 2, 2001

Endocarditis Due to Streptococcus mitis With High-Level Resistance to Penicillin and Ceftriaxone

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;285(17):2195. doi:10.1001/jama.285.17.2195

To the Editor: Antimicrobial resistance is an increasing problem in the treatment of infections due to Streptococcus pneumoniae.1 Such resistance has also recently been reported in the United States among the viridans group of streptococci, especially Streptococcus mitis.2 We report a case of subacute bacterial endocarditis in a child, resulting from an infection caused by S mitis that was fully resistant to penicillin and ceftriaxone.