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July 11, 2001

Pneumococcal Vaccination in Adults

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;286(2):166-167. doi:10.1001/jama.286.2.166

Letter to the Editor: Ms Robinson and colleagues recently summarized data from the Active Bacterial Core Surveillance/Emerging Infections Program Network to understand the epidemiology of Streptococcus pneumoniae in invasive pneumococcal disease (IPD).1 The authors state, "We sought to estimate the expected effect of the recently licensed vaccine [7-valent pneumococcal conjugate vaccine] . . . " and, "More than half of these cases [IPD] occurred in adults who had an indication for pneumococcal polysaccharide vaccination . . . " However, it is important to note that the "expected effect" and actual effectiveness of pneumococcal vaccination may differ markedly.