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September 12, 2001

Role of Immune Function in Human Papillomavirus Infection

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;286(10):1173-1174. doi:10.1001/jama.286.10.1173

To the Editor: Dr Moscicki and colleagues1 found a strong association between the frequency of sexual behavior and human papillomavirus (HPV) infection. They claim that this "supports the hypothesis that HPV is a sexually transmitted virus and that most ‘new' infections in young females are predominantly due to exposure, rather than the ‘transient' upregulation of latent infections in nonimmunocompromised hosts."