Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
In Reply: Mr Foley and colleagues offer an
insightful follow-up to our report indicating increased risk for SDB with ApoE ∊4. In their study, ApoE ∊4 did not increase
risk for SDB in Japanese-American men aged 79 to 97 years. Although additional
studies are needed to confirm our finding, the discrepancy is most likely
due to age, population, and design differences. As pointed out by Foley et
al, men aged 79 to 97 years comprised their sample; our study is based on
a community sample of men and women aged 30 to 60 years.
Mignot E, Murphy, Jr GM, Young T. Relationship Between Apolipoprotein E ∊4 and Sleep-Disordered Breathing at Different Ages—Reply. JAMA. 2001;286(12):1447–1448. doi:10.1001/jama.286.12.1447
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