Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
To the Editor: Dr Spechler and colleagues1 found that 62% of patients who underwent surgical
therapy for gastroesophageal reflux disease (GERD) later required antisecretory
therapy. However, their study design limits the conclusions on treatment efficacy
because they did not follow their patients longitudinally over the entire
follow-up period, but only assessed them at 1 point 10 to 13 years after the
surgery or the initial medical treatment period. Patient outcomes during the
decade preceding the time of the study are not known. This is a problem, particularly
in assessing efficacy as measured by symptom and medication questionnaires,
endoscopy, and pH monitoring.
Harary AM. Medical vs Surgical Treatment of Gastroesophageal Reflux. JAMA. 2001;286(14):1709–1712. doi:10.1001/jama.286.14.1709
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: