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October 10, 2001

Medical vs Surgical Treatment of Gastroesophageal Reflux—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;286(14):1709-1712. doi:10.1001/jama.286.14.1709

In Reply: The goal of our study was to determine the long-term outcome for patients who had participated in a randomized trial of medical and surgical therapies for GERD in the 1980s. Except for the data collected on mortality and on invasive procedures performed for the treatment of GERD since the original trial, the follow-up study involved clinical tests and questionnaires administered at 1 point, some 10 to 13 years after randomization. On the basis of those results, Dr Harary is correct that one cannot make valid conclusions regarding differences between the treatment groups prior to the conduct of the follow-up study. However, we made no such conclusions anywhere in our article.