Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
To the Editor: Because perception thresholds
to gastrointestinal distension can be affected by stress,1
psychological factors may play an important role in visceral perception. The
cerebral evoked potential (CEP), which originates from the processing of afferent
neural pathways, may reflect such higher-level processing of painful stimuli.
Topographic study suggests that early peaks of CEP originate from deep central
brain structures, whereas later peaks originate from the cortex.2
We have previously found that patients with functional dyspepsia have shorter
peak latency of the late CEP component by esophageal electrical stimulation
(ES), suggesting that patients with dyspepsia may have an altered central
processing of visceral perception.3 Although
Shagass and Schwartz4 reported a relationship
between neuroticism and peak latencies for somatosensory evoked potentials,
it is not clear how CEP responses may relate to visceral perception. We investigated
the hypothesis that late CEP responses to visceral stimulation may be related
to personality traits.
Kanazawa M, Fukudo S, Nomura T, Hongo M. Electrophysiological Correlates of Personality Influences in Visceral Perception. JAMA. 2001;286(16):1974–1975. doi:10.1001/jama.286.16.1969
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