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November 7, 2001

Effect of Condoms on Reducing Genital Herpes Transmission

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;286(17):2095-2096. doi:10.1001/jama.286.17.2091

To the Editor: Dr Wald and colleagues1 report an intriguing finding that condom use may be protective against herpes simplex virus type 2 (HSV-2) transmission from men to women but not from women to men. The authors suggest 2 explanations for this apparent paradox: first, that men could have had increased contact with sites of high viral shedding other than the vagina, and second, that "men may be more likely to limit condom use to situations with higher risk acquisition."

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