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November 21, 2001

Exposure to Soy-Based Formula in Infancy

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;286(19):2402-2403. doi:10.1001/jama.286.19.2398

To the Editor: Dr Strom and colleagues1 found no differences in later pubertal maturation or growth between infants who had been fed soy-based vs milk-based formula. However, this does not prove that soy-based formulas are safe. In fact, the authors found that infants who had been given soy-based formula later used more asthma and allergy medications (P = .047 and .08 for female and male subjects, respectively). This important observation was not mentioned in the abstract, which stated that "[n]o statistically significant differences were observed . . . for more than 30 outcomes."1