Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
To the Editor: Hyperglycemia has been associated
with the atypical antipsychotic agents clozapine and olanzapine,1
and a recent case report described diabetic ketoacidosis associated with olanzapine
in a pediatric patient.2 To gain further
insight into the association between hyperglycemia and these 2 drugs in the
pediatric population, we queried the US Food and Drug Administration (FDA)
MedWatch drug surveillance system to identify cases occurring in patients
younger than 19 years.
Koller E, Malozowski S, Doraiswamy PM. Atypical Antipsychotic Drugs and Hyperglycemia in Adolescents. JAMA. 2001;286(20):2547–2548. doi:10.1001/jama.286.20.2542
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