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December 19, 2001

Persistent Macrocytosis Following Abstinence From Chronic Alcohol Use

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;286(23):2946. doi:10.1001/jama.286.23.2940

To the Editor: Because the mean corpuscular volume (MCV) of red blood cells may be elevated in as many as 89% of patients with chronic alcohol use1 this test is often used as a marker of ongoing alcohol abuse.2 It is not known, however, whether the MCV returns to normal after cessation of chronic alcohol use.