Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
In Reply: Our study was designed to compare
directly the 2 salmeterol-treated groups. The group that received placebo
(salmeterol) was limited in enrollment to safely evaluate whether the rate
of failure following reduction and elimination of ICs would be similar to
that reported by others, and to document that the patients enrolled required
IC therapy to maintain adequate asthma control. As Drs Fowler and Lipworth
acknowledge, both of these outcomes were observed.
Lemanske, Jr RF. Salmeterol and Inhaled Corticosteroids in Patients With Persistent Asthma—Reply. JAMA. 2001;286(24):3075–3078. doi:10.1001/jama.286.24.3075
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