Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor
To the Editor: I have several concerns about
Dr Inzucchi's review1 of oral antihyperglycemic
therapy. First, he described the effects of various agents only in terms of
comparison with placebo rather than with baseline values. This way of presenting
the data can be misleading. In diabetes clinical trials, glycemic control
frequently deteriorates in the placebo group, which amplifies the efficacy
of active therapy.
Mikhail N. Drug Therapy for Patients With Type 2 Diabetes. JAMA. 2002;287(13):1645–1646. doi:10.1001/jama.287.13.1645
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