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April 24, 2002

Chelation Therapy for Patients With Ischemic Heart Disease

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor

JAMA. 2002;287(16):2077-2078. doi:10.1001/jama.287.16.2073

To the Editor: Dr Knudtson and colleagues1 reported that chelation therapy was ineffective in treating patients with ischemic heart disease. However, some of their findings suggest that chelation may do some good.

First, there is some evidence that magnesium and ascorbic acid, which are common components of chelation therapy, may have beneficial effects.2,3 Patients in both the treatment and placebo groups received magnesium and ascorbic acid, and both groups improved.