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May 22/29, 2002

Does Marijuana Use Cause Long-term Cognitive Deficits?—Reply

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor

JAMA. 2002;287(20):2652-2654. doi:10.1001/jama.287.20.2652

In Reply: Dr Solowij and colleagues provide reassurance regarding their extensive efforts to control for possible confounds. Our similar study1 of equally long-term cannabis users agrees with theirs in finding cognitive impairment hours to days after discontinuing cannabis. However, our studies still disagree on one important point: Solowij et al found increasing cognitive impairment with increasing duration of cannabis use, whereas we did not.