Copyright 2002 American Medical Association. All Rights Reserved.
Applicable FARS/DFARS Restrictions Apply to Government Use.2002
To the Editor: Dr Bodary and colleagues1 found that leptin contributed to arterial thrombosis
following photochemical vascular injury in mice. Recently, Konstantinides
et al2 reported similar results with the
ferric chloride model of carotid artery injury. A common factor of these findings
may be the ability of leptin to enhance platelet aggregation through the stimulation
of the long form of its receptor on the platelet membrane.2-4
Corica F, Corsonello A, Perticone F. Effects of Leptin on Platelet Function in Obese Patients. JAMA. 2002;288(3):313–314. doi:10.1001/jama.288.3.311
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