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August 7, 2002

Modes of Transmission of Hemorrhagic Fever

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor

JAMA. 2002;288(5):571. doi:10.1001/jama.288.5.571

To the Editor: In their Consensus Statement on hemorrhagic fever viruses that may be used as biological weapons, Dr Borio and colleagues1 state, "There are no reported cases of person-to-person or nosocomial spread of flaviviruses." At least 2 cases of nosocomial transmission of dengue (a flavivirus) have been reported in the medical literature: one through a needlestick injury2 and the other through bone marrow transplantation.3 These events, although rare, suggest that nosocomial spread may also be possible for a more feared flavivirus—yellow fever.