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August 14, 2002

Erectile Dysfunction and Hepatitis C Virus Infection

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor

JAMA. 2002;288(6):698-699. doi:10.1001/jama.288.6.693

To the Editor: Hepatitis C virus (HCV) infection has been associated with immune-mediated manifestations such as glomerulonephritis, thyroiditis, peripheral neuropathy, sicca syndrome, arthritis, and mixed cryoglobulinemia.1,2 Although erectile dysfunction has been anecdotally reported in patients with HCV-related chronic hepatitis, it is unclear whether this is related to superimposed liver failure, to interferon alfa treatment, or to the disease process itself.3