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January 11, 2012

Supplementation in Acute Lung Injury

Author Affiliations

Author Affiliations: Department of Anesthesiology and Intensive Care Medicine, Tübingen University Hospital, Tübingen, Germany (Drs König and Rosenberger) (klemens.koenig@kgu.de); and Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Boston, Massachusetts (Dr Mirakaj).

JAMA. 2012;307(2):144-146. doi:10.1001/jama.2011.1984

To the Editor: The study by Dr Rice and colleagues investigated the effect of enteral n-3 fatty acids, GLA, and antioxidants on ALI.1 The authors demonstrated that patients in the treatment group had a higher mortality rate and fewer days free from the ventilator, intensive care unit, and organ failure compared with the control group. These results are in contrast to previous studies demonstrating a protective role for n-3 fatty acids during sepsis or acute respiratory distress syndrome.2