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April 9, 2008

Prevalent Vertebral Fracture and the Risk of Incident Vertebral Fracture

JAMA. 2008;299(14):1666-1667. doi:10.1001/jama.299.14.1666-b

To the Editor: Dr Cauley and colleagues1 reported that women aged 65 years and older in the Study of Osteoporotic Fractures who had prevalent vertebral fracture had more than a 4-fold increased odds of subsequent incident vertebral fracture in the next 10 years. This finding is consistent with the Framingham Study2 for which we were coauthors, demonstrating the importance of prevalent vertebral fracture as a risk factor for subsequent vertebral fracture.