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Lab Reports
April 4, 2012

New Antiseizure Agents

JAMA. 2012;307(13):1357. doi:10.1001/jama.2012.370

Two compounds that block certain calcium channels in the brain can suppress absence-like epilepsy seizures in rats, report researchers at the University of British Columbia, in Vancouver, Canada, and colleagues (Tringham E et al. Sci Transl Med. 2012;4[121]:121ra19).

In humans, most absence or “petit mal” seizures are treated with medications that act on multiple targets, do not completely control the seizures, and can cause considerable adverse effects.