One of the most complex challenges clinicians and their patients with breast cancer face is to determine a treatment plan for disease with relatively favorable prognosis. Advances in treatment have improved life expectancy, but these advances have come at a steep price because treatments impose substantial morbidity and burden on patients and their families. Concerns about the potential harm of treatments have increased as population-based screening has identified an increased number of breast cancer patients with relatively favorable prognosis.1 These concerns have motivated several initiatives to reduce morbidity and treatment burden.
Katz SJ, Morrow M. The Challenge of Individualizing Treatments for Patients With Breast Cancer. JAMA. 2012;307(13):1379–1380. doi:10.1001/jama.2012.409
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