Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor
In Reply.—Our interpretation of the results
of the Dietary Alternatives Study are regarded as "misleading" by Dr Ornish,
who quotes his Lifestyle Heart Trial.1We
disagree with this statement. Our purpose was to compare lipoprotein and metabolic
response to 4 different diets of increasing fat restriction with targets ranging
from 30%, 26%, 22%, and 18% of energy intake as fat. No other interventions
were undertaken. In contrast, Ornish studied the effects of multiple interventions
to reduce coronary artery narrowing. Thus, the purposes and interpretation
of the 2 studies are different.
Knopp RH, . Serum Lipids After a Low-Fat Diet—Reply. JAMA. 1998;279(17):1345–1346. doi:10-1001/pubs.JAMA-ISSN-0098-7484-279-17-jbk0506
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