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May 13, 1998

Hypoglycemia From Glipizide and Glyburide

Author Affiliations

Copyright 1998 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1998

JAMA. 1998;279(18):1441-1443. doi:10-1001/pubs.JAMA-ISSN-0098-7484-279-18-jac80006

To the Editor.—The study by Dr Burge and colleagues1 helps to establish that in the debate over the possible risks of hypoglycemia with sulfonylureas, a concern should not be the drug but rather the recipient. Indeed, the characteristic of the patients with type 2 diabetes mellitus included in the study is highlighted by a simple key word, healthy. Exclusion criteria were the presence of severe cardiovascular, gastrointestinal, renal, or hepatic disease, malignancies, or concurrent medications. Quite the contrary, the typical patient with type 2 diabetes is not a healthy one.

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