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June 17, 1998

Rapid Opioid Detoxification

Author Affiliations

Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor

JAMA. 1998;279(23):1871-1872. doi:10.1001/jama.279.23.1871

To the Editor.—In an otherwise excellent review of rapid and ultrarapid opioid detoxification techniques by Drs O'Connor and Kosten,1we would like to point out 3 major errors and make 1 point of clarification.

First, the anesthesia mortality rate of 1 in 1185 to 1 in 6789 is out-of-date, and was cited from a textbook published in 1992. Current anesthesia mortality among the American Society of Anesthesiologists' physical classification I and II patients, into which the vast majority of young people addicted to opiates almost undoubtedly fit, is rare.2,3

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