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July 1, 1998

Serologic Evidence for Mother-to-Child Transmission of Kaposi Sarcoma–Associated Herpesvirus Infection

Author Affiliations

Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor

JAMA. 1998;280(1):31-32. doi:10-1001/pubs.JAMA-ISSN-0098-7484-280-1-jbk0701

To the Editor.— Kaposi sarcoma (KS)–associated herpesvirus (KSHV, or human herpesvirus 8 [HHV-8]) has been causally linked to KS.1,2 In the United Kingdom and the United States, sex between men may be an important route of transmission of HHV-8, because this is the main behavioral risk factor for KS in human immunodeficiency virus (HIV)–seropositive subjects. However, in parts of Africa where KS was seen in children even before the advent of the acquired immunodeficiency syndrome (AIDS),3 other routes of transmission also must occur.4