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November 4, 1998

Simian Virus 40–Contaminated Polio Vaccine and Cancer Rates

Author Affiliations

Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor

JAMA. 1998;280(17):1481-1482. doi:10-1001/pubs.JAMA-ISSN-0098-7484-280-17-jbk1104

To the Editor.— In their report on contamination of poliovirus vaccine with simian virus 40 (SV40), Dr Strickler and colleagues1 mistakenly claim that "earlier studies of cancer risk following exposure to SV40-contaminated vaccine were generally limited by small sample size or short follow-up." I refute this suggestion and contend that my report,2 which they include in this group, neither was of limited sample size nor was it a short follow-up as arguably the others they refer to were.