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November 18, 1998

The APOE-∊4 Allele and Alzheimer Disease Among African Americans, Hispanics, and Whites

Author Affiliations

Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor

JAMA. 1998;280(19):1661-1663. doi:10-1001/pubs.JAMA-ISSN-0098-7484-280-19-jbk1118

To the Editor.—While Dr Tang and colleagues1 report an increased incidence of AD in African Americans and Hispanics compared with whites, there is "no accepted definition of race,"2 since the "classification into races has proved to be a futile exercise."3 Ethnicity has been suggested as a substitute for race or even as an alternative to it, but the federal designation of "race/ethnicity" has unhelpfully combined what can be neither lumped nor split.