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December 16, 1998


Author Affiliations

Margaret A.WinkerMDIndividualAuthorPhil B.FontanarosaMD, Senior EditorsIndividualAuthor

JAMA. 1998;280(23):1992-1993. doi:10-1001/pubs.JAMA-ISSN-0098-7484-280-23-jbk1216

In Reply.—Our response to Drs Trippoli and Messori is premised on the inevitability of choices in the health sector. More often than not, clinicians, managed care organizations, and AIDS drug assistance program managers must make urgent decisions based on the best available information. They do not have the luxury of demanding proof beyond a reasonable scientific doubt or of suspending judgment in anticipation of better experimental data. Inaction itself is a decision with consequences for patients and society.