Copyright 1998 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1998
In Reply.—Antimicrobial resistance in S typhi and vaccinology have developed rapidly in recent
years. Drs Atkins and Gottlieb point out that quinolone resistance to S typhi is an evolving problem in South Asia and that susceptibility
testing should be performed. In the United States, the standard of care is
to determine susceptibility for blood isolates. However, these developments
emphasize the need for antimicrobial surveillance in areas where testing is
not routine and where quinolones are routinely used. For the patient we presented
at Grand Rounds, quinolones were not an option because of pregnancy.
Zenilman JM. Emerging Drug Resistance and Vaccination for Typhoid Fever—Reply. JAMA. 1998;279(8):579–580. doi:10-1001/pubs.JAMA-ISSN-0098-7484-279-8-jbk0225
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