Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor
To the Editor.—Dr Mercer and colleagues
of the National Institute of Child Health and Human Development Maternal-Fetal
Medicine Units Network1 have recently recommended
that women with expectantly managed preterm premature rupture of membranes
(PPROM) remote from term (≤32 weeks) should receive a specific regimen
of antimicrobials to reduce infant morbidity. Whereas we applaud their efforts,
we cannot agree that the conclusion should necessarily follow from their results
given contemporary perinatal practice.
Cimolai N. Antibiotic Therapy for Premature Rupture of Membranes to Prevent Respiratory Distress Syndrome. JAMA. 1998;279(10):748–749. doi:10-1001/pubs.JAMA-ISSN-0098-7484-279-10-jac80000
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