[Skip to Content]
[Skip to Content Landing]
October 3, 1931

Experiments on the Etiology of the Influenza Epidemic of 1928-1929.

JAMA. 1931;97(14):1025. doi:10.1001/jama.1931.02730140061035

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This is another attempt to establish a possible relationship between a particular group of bacteria and influenza. The authors' conclusions are recorded in thirty-eight items in the summary. In brief, it is asserted that material transferred from human cases of "influenza" has produced an influenzalike disease in monkeys; that pure cultures of Pfeiffer's bacillus and B. pneumosintes will not produce such a condition; that an acute infection of the upper respiratory tract resembling influenza has been induced by the use of cultures of a pleomorphic "hemophilic" streptococcus isolated from the blood of a human case of "influenza"; that "rough" colonies of this organism are more virulent than "smooth" colonies; and, finally, that the pleomorphic streptococci studied were "not improbably... etiologically related to the influenza outbreak in Chicago in the winter of 1928-1929." Proper evaluation of the experimental data is difficult, partly because of the enormous amount of material and partly

First Page Preview View Large
First page PDF preview
First page PDF preview