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Article
October 24, 1931

The Thomsen Hemagglutination Phenomenon: Production of a Specific Receptor Quality in Red Corpuscles by Bacterial Activity.

JAMA. 1931;97(17):1249. doi:10.1001/jama.1931.02730170061042

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Abstract

The author has prepared in monographic form an elaboration of the original studies of a peculiar agglutination phenomenon of red blood cells now known as the Thomsen hemagglutination phenomenon. In the first chapter he briefly considers some of the fundamental points concerning hemagglutination. The work then deals with the specific propagative agent discovered by Oluf Thomsen in 1927 that has a characteristic effect on the iso-agglutinability of human blood corpuscles. From the summary of the author's investigation it seems possible that human blood corpuscles of any group may be changed through the influence of a propagative, transmissible agent so that they become agglutinable in any human serum and the serum from the same individual. The general properties of the corpuscles are not changed in the transformation process but differ from normal ones only in the altered agglutinability. As a result of the author's investigations he regards the transformation as an

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