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Article
November 14, 1931

THE COFFEY-HUMBER EXTRACT OF SUPRARENAL CORTEX SUBSTANCE: A CLINICAL STUDY OF FOUR HUNDRED AND FIFTEEN PATIENTS WITH MALIGNANT TUMORS WHO RECEIVED EXPERIMENTAL INJECTIONS

Author Affiliations

LOS ANGELES

JAMA. 1931;97(20):1457-1463. doi:10.1001/jama.1931.02730200033008

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Abstract

This paper is presented as a brief summary of the results of a clinical and pathologic study conducted by the W. K. Kellogg Foundation. Four hundred and fifteen persons who had carcinoma or sarcoma were given subcutaneous injections of suprarenal cortex substance extract by representatives of Drs. Walter B. Coffey and John D. Humber, and were observed and examined by physicians of the foundation. Case abstracts made by former physicians were furnished by these patients on beginning experimental injections. The majority of the patients first had received injections of the extract at the Los Angeles Central Coffey-Humber Clinic and were transferred with their records to the Kellogg Foundation. Some patients were accepted by the foundation for their first injections of the extract.

The majority of the patients were ambulatory. They received injections of the extract and made progress reports at the foundation clinic at Boyle and Michigan avenues. They lived

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