It is a well established fact that many symptoms which have been treated empirically by the administration of sedatives, analgesics, massage, various types of heliotherapy, electrotherapy and other types of physical therapy are merely the manifestations of infection located in organs more or less remote from the point at which these symptoms are made manifest.
For many years we physicians were in the habit of speaking more or less perfunctorily of attacks of "biliousness," "indigestion," "dyspepsia," "rheumatism," "neuritis," "arthritis," "autointoxication," and "reflex pains," with some variations or ramifications of these conditions. We used to speak of, think of, and treat many patients for so-called muscular rheumatism, sciatica, lumbago and various neuralgias. We can all remember many instances in which internal organs were innocently accused of being the general causal factors, and we can all recall surgical operations for the removal of these organs, which have since proved unnecessary. Since we
HIRSCHMAN LJ. FOCAL INFECTION OF ANAL ORIGIN. JAMA. 1931;97(22):1609–1611. doi:10.1001/jama.1931.02730220031007
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