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December 5, 1931

Benzol (Benzene) Poisoning: A New Investigation of the Toxicity of Benzene and Benzene Impurities.

JAMA. 1931;97(23):1733. doi:10.1001/jama.1931.02730230075033

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Benzene poisoning has become one of the most serious hazards of modern industry. As pointed out in the preface to this report, conditions other than benzene poisoning simulate it so closely that the diagnosis is frequently confused. Indeed, recently the similarity of benzene poisoning to agranulocytosis has been a special problem. The part played in the production of pathologic conditions by impurities in benzene has not been adequately presented, and the range of symptoms has not been properly recorded. The review of the subject by Dr. McCord presents new evidence, provides a practical review of present knowledge, and affords orientation in this field. It includes much new experimental evidence and is exceedingly practical in its recommendations for treatment and particularly for prevention. Finally, it is supplemented by an excellent bibliography covering the literature on the subject.

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