There has been comparatively little written on corneal ulcers in the last few years, because practically nothing new has been developed on this subject. Evans1 states that out of 700 old blind people he found that 45 were blind because of corneal opacities. Most corneal opacities are caused by ulceration, and, when one takes into consideration the vast number of corneal opacities caused by ulceration that produce partial blindness or only slight reduction in vision, one is impressed with the necessity for further study in the management of this disease.
The behavior of the cornea in health, disease and injury has been quite well established by careful investigators, and while there are still some existing conditions that must be viewed through a mist of indefinite knowledge, the bridging of the latter has led to a very satisfactory understanding of the cornea in health and in disease.
NORMAL AND PATHOLOGIC
NUGENT OB. THE PATHOLOGY AND TREATMENT OF CORNEAL ULCERS. JAMA. 1932;98(3):207–212. doi:10.1001/jama.1932.02730290023006