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To the Editor:
—In The Journal, July 25, 1931, page 244, there appeared a preliminary report on the treatment of hemophilia (in males) with female sex hormone, by Dr. Carroll LaFleur Birch of Chicago. Birch also published a report on the treatment of two patients with high grade hemophilia by means of ovarian extract—two brothers, one aged 10 years and one older, who, after treatment with ovarian extract, also received a fresh human ovarian transplant into the anterior abdominal wall (Proc. Soc. Exper. Biol. & Med.28:752 [April] 1931). In connection with this report it might be of interest to note that F. Wibaut, an ophthalmologist of Amsterdam, used female hormone in the treatment of retinitis pigmentosa because this condition occurred much more frequently and more severely in males, since 1927 (Deutsche med. Wchnschr.57:1739 [Oct. 9] 1931).Snapper (Geneeskundige Kring Amsterdam) treated three male patients with Buerger's
Goldstein HI. SEX HORMONES AND OVARIAN EXTRACTS IN THE TREATMENT OF HEMOPHILIA. JAMA. 1932;98(3):249. doi:10.1001/jama.1932.02730290065027
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