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The author starts with the same thesis that every deficiency of nutrition, whether of quantitative or qualitative nature, is accompanied by an increased susceptibility to infection and a lowered resistance. On the basis of a detailed review of the observations now available, the author concludes that "the rôle of vitamin A as an anti-infectious factor appears indisputable; that vitamin B is hardly playing any rôle in this respect; that the opinions as to the importance of vitamin C in this respect are divergent, though it is most likely that this vitamin is hardly of any particular importance to the organism as far as resistance to infection goes; and, finally, that there is nothing directly suggestive of vitamin D having any resistance-increasing effect, and that for that matter the clinical material is less suitable for information on this point than is the clinical material concerning the other vitamins." He points out
Experimental Studies on the Course of Paratyphoid Infections in Avitaminotic Rats with Special Reference to Vitamin A Deficiency. JAMA. 1932;98(3):254. doi:10.1001/jama.1932.02730290070032
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