The etiology of senile cataract remains obscure despite the efforts that have been made to establish a cause or causes. Up to the present no certain knowledge has been obtained of the common causes of this condition. As a matter of fact there is probably no one cause but a multiplicity of them. Theories there are in abundance, but too frequently they have been advanced on an inadequate basis. If the etiology of senile opacity of the lens is to be discovered, the problem must be approached in a scientific manner. Little by little, work must be done and the results rejected or fitted to other results, until finally these observations may be pieced together and the true explanation for this condition established.
In a review of the literature one is astounded to find the great number of theories that have been advanced. Some of these are reasonable and others
O'BRIEN CS. HYPERGLYCEMIA IN PERSONS WITH ADVANCED SENILE CATARACT. JAMA. 1932;98(4):284–290. doi:10.1001/jama.1932.02730300014004
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