There has been increasing recognition of the importance of a causal diagnosis in conjunctivitis in recent years, due no doubt to the fact that specific chemotherapy has been made available for a number of important types of the disease. In addition to its value as a guide to therapy, causal determination is important for prognosis, since it is obviously often of great value to be able to predict accurately the clinical course and outcome of a conjunctival infection.
In routine office practice facilities for bacteriologic and pathologic examination are frequently not available, and advantage must therefore be taken of such causal indications as can be obtained from careful gross and slit lamp examination of the conjunctiva and the contiguous structures. It is not generally recognized that reliable differentiation of many of the major types of conjunctivitis can be made on clinical examination alone, independently of laboratory observations. The following report
THYGESON P. CLINICAL SIGNS OF DIAGNOSTIC IMPORTANCE IN CONJUNCTIVITIS. JAMA. 1947;133(7):437–441. doi:10.1001/jama.1947.02880070001001
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