The physiologic basis of uterine bleeding in primates is a subject of perennial discussion. In this article I propose to present a series of related facts pertaining to menstruation. Some of these facts are so recently acquired that it is impossible to incorporate them with certainty in the older views of the subject. This amounts to saying that new discoveries remain to be made.
The physiologist recognizes that the first step in the explanation of menstrual mechanisms is an understanding of the morphologic characteristics of that part of the peripheral vascular tree which undergoes the menstrual process. This is particularly true today, since newer knowledge of a histologic nature makes it necessary to revise and enlarge the existing ideas concerning menstruation. On one hand Danish workers, notably Okkels and his students Schlegel and Dalgaard, have recently demonstrated in the human endometrium the probable presence of numerous arteriovenous anastomoses (Okkels, 1947;
REYNOLDS SRM. THE PHYSIOLOGIC BASIS OF MENSTRUATION: A SUMMARY OF CURRENT CONCEPTS. JAMA. 1947;135(9):552–557. doi:10.1001/jama.1947.02890090008003
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