Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor
To the Editor.—Dr Mahalingam and Ottlinger1 report the case of an elderly patient with angina
pectoris on exertion associated with discrepancies in laboratory values comprising
an increase in quantitative cardiac troponin T (cTnT) and in total and MB
creatine kinase (CK) and a negative result for cTnT rapid test. They conclude
that the cTnT rapid test failed to diagnose myocardial infarction in this
patient. However, we propose another hypothesis: that the patient had no myocardial
infarction but only a macro CK in his serum.
Belmin J, Medjahed S, Bruhat A. False-Negative Qualitative Troponin T. JAMA. 1998;279(16):1262–1263. doi:10-1001/pubs.JAMA-ISSN-0098-7484-279-16-jac80007
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